Understanding how hormones affect nighttime blood pressure in obese individuals
Natriuretic Peptide-Renin-Angiotensin-Aldosterone System Rhythm Axis and Nocturnal Blood Pressure
This study is looking at how certain hormones and blood pressure patterns work together in people who are obese, and it aims to find out if taking medication at specific times can help better control nighttime blood pressure for those individuals.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project ID | NIH-11004134 on NIH RePORTER |
What this research studies
This research investigates the relationship between natriuretic peptides, the renin-angiotensin-aldosterone system, and nighttime blood pressure patterns in obese individuals. It aims to understand how these hormones interact and how their rhythms can be synchronized to improve blood pressure control. The study will explore the effects of administering medication at specific times to align these biological rhythms, potentially leading to better management of nocturnal blood pressure. Participants may undergo monitoring and receive tailored treatments based on their individual responses.
Who could benefit from this research
Good fit: Ideal candidates for this research are obese adults who experience high nighttime blood pressure and are currently being treated for hypertension.
Not a fit: Patients who are not obese or do not have hypertension may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved blood pressure management and reduced cardiovascular risks for obese individuals.
How similar studies have performed: Previous research has shown promising results in synchronizing biological rhythms to improve health outcomes, suggesting potential for success in this approach.
Where this research is happening
Birmingham, United States
- University of Alabama at Birmingham — Birmingham, United States (Active)
Researchers
- Principal investigator: Arora, Pankaj — University of Alabama at Birmingham
- Study coordinator: Arora, Pankaj
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.