Understanding how hormones affect immune cells in the uterus
Goods - Proj 1
This study looks at how the immune system and hormones work together in women's reproductive health, especially during the menstrual cycle, to understand how immune cells help keep the uterus healthy and how this might help with conditions like endometriosis.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dartmouth College NIH-funded |
| Lab location | 1 site (Hanover, United States) |
| Project ID | NIH-10852730 on NIH RePORTER |
What this research studies
This research investigates the interactions between the endocrine and immune systems in the female reproductive tract, particularly focusing on how immune cells respond to hormonal changes throughout the menstrual cycle. By employing a systems-biology approach, the study aims to explore the roles of macrophages in maintaining a healthy uterine environment while also addressing conditions like endometriosis. The research will analyze how these immune cells adapt to hormonal fluctuations and their implications for reproductive health. Patients may benefit from insights that could lead to improved treatments for hormone-related reproductive disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research include women experiencing reproductive health issues, particularly those with endometriosis or other hormone-related disorders.
Not a fit: Patients who do not have any reproductive health issues or hormonal disorders may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for conditions like endometriosis, improving reproductive health outcomes for many women.
How similar studies have performed: Other research has shown success in understanding immune responses in reproductive health, suggesting that this approach could yield valuable insights.
Where this research is happening
Hanover, United States
- Dartmouth College — Hanover, United States (Active)
Researchers
- Principal investigator: Goods, Brittany Anne — Dartmouth College
- Study coordinator: Goods, Brittany Anne
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.