Understanding how hormonal changes during perimenopause affect trauma responses in Black women
Neuroendocrine Mechanisms Underlying Perimenopausal Risk for Trauma-Related Hyperarousal in Black Women
This study is looking at how hormonal changes during the perimenopause can affect how Black women from urban, low-income backgrounds respond to trauma and fear, helping us understand their unique experiences better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11044144 on NIH RePORTER |
What this research studies
This research investigates the impact of hormonal changes during the perimenopausal phase on trauma-related hyperarousal in Black women, particularly those from urban, low socioeconomic backgrounds. It aims to understand how fluctuations in the hormone estradiol (E2) influence responses to trauma and fear. The study will utilize clinical interviews, psychophysiological assessments, neuroimaging, and neuroendocrinological methods to gather comprehensive data on these interactions. By focusing on this specific population, the research seeks to fill a critical gap in knowledge regarding the unique vulnerabilities faced by perimenopausal Black women exposed to trauma.
Who could benefit from this research
Good fit: Ideal candidates for this research are Black women who are in the perimenopausal stage and have experienced trauma.
Not a fit: Patients who are not Black women or who are not in the perimenopausal stage may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for trauma-related mental health issues in perimenopausal Black women.
How similar studies have performed: While there has been research on trauma and hormonal influences, this specific focus on perimenopausal Black women is relatively novel and underexplored.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Michopoulos, Vasiliki — Emory University
- Study coordinator: Michopoulos, Vasiliki
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.