Understanding how HIV viral loads change after stopping treatment
Modeling of Viral Load Trajectories for HIV Cure Research
This study is looking at how HIV levels change in people after they stop taking their medication, to help find ways to potentially cure HIV or keep it under control without needing ongoing treatment, and we’d love for patients to share their experiences and health information to help us understand this better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard Pilgrim Health Care, INC. NIH-funded |
| Lab location | 1 site (Canton, UNITED STATES) |
| Project ID | NIH-10892652 on NIH RePORTER |
What this research studies
This research investigates the patterns of HIV viral load changes in patients after they stop antiretroviral therapy (ART). It aims to identify the factors that influence how quickly the virus rebounds and stabilizes in the body, which is crucial for developing strategies to achieve an HIV cure or long-term remission without ongoing treatment. By analyzing data from various clinical trials, the study seeks to overcome challenges in understanding these viral load trajectories and their predictors. Patients may contribute to this research by providing data on their viral load levels and health status during treatment interruptions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who are considering or have undergone treatment interruption.
Not a fit: Patients who are not living with HIV or those who are not eligible for treatment interruption may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for curing HIV or allowing patients to remain off ART without viral rebound.
How similar studies have performed: Previous research has shown promise in understanding viral load dynamics in HIV, but this approach aims to fill critical gaps in current knowledge.
Where this research is happening
Canton, UNITED STATES
- Harvard Pilgrim Health Care, INC. — Canton, United States (Active)
Researchers
- Principal investigator: Wang, Rui — Harvard Pilgrim Health Care, INC.
- Study coordinator: Wang, Rui
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.