Understanding how HIV treatment affects HPV-related oral cancer progression
Official title: Understanding the Role of HAART in the Progression of HPV-Associated Oral Cancer
Funded at Pennsylvania State Univ Hershey Med Ctr · NIH-11331252 · Data updated 2026-11-12
This grant looks at how HAART, the HIV treatment, might influence the development and progression of HPV-related oral cancer and which patients could be most at risk.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State Univ Hershey Med Ctr NIH-funded |
| Lab location | 1 site (Hershey, United States) |
| Project start | July 11, 2022 |
| Project end | May 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $536,210 |
| NIH project number | 5R01DE032212-05 |
| Project ID | NIH-11331252 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals with HPV-positive head and neck cancer, particularly those living with HIV/AIDS, may be eligible for future studies or related trials.
✕Less likely to help
Patients without HPV-positive head and neck cancer or without HIV infection may not experience direct benefits from this specific research.
What this research studies
This project uses an in vitro model to study how HPV-related oral cancer progresses, with special attention to people living with HIV. It seeks to connect HIV status, cancer biology, and responses to standard therapies like radiation and chemotherapy. The research aims to identify biological markers and critical steps in progression that could guide future prevention, early detection, and tailored treatment for patients with HIV who develop HPV-positive head and neck cancer.
Why it matters
Potential benefit: Could lead to more personalized care and better outcomes for patients with HIV who develop HPV-related oral cancer.
How similar studies have gone: Previous work shows HPV-positive cancers have distinct biology and treatment responses, supporting potential benefits of this line of investigation.
Where this research is happening
-
Pennsylvania State Univ Hershey Med Ctr
Hershey, United States Active
Researchers
- Principal investigator: Meyers, Craig M — Pennsylvania State Univ Hershey Med Ctr
- Study coordinator: Meyers, Craig M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.