Understanding how HIV persists and can be eliminated
Simulating persistence and elimination of the HIV reservoir
This study is working on a way to better understand the hidden HIV reservoir in people living with HIV, which keeps the virus around, and aims to find new strategies that could help lead to a cure.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Fred Hutchinson Cancer Center NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10894899 on NIH RePORTER |
What this research studies
This research focuses on developing a mathematical model to better understand the HIV reservoir, which is the source of persistent infection in individuals living with HIV. By analyzing diverse experimental data, the project aims to simulate the processes that lead to the creation and elimination of this reservoir. The research is part of a training program for Dr. Reeves, who will gain expertise in virology, immunology, and phylogenetics, supported by a team of experienced mentors. The ultimate goal is to contribute to the development of strategies that could lead to an HIV cure.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who are currently on antiretroviral therapy.
Not a fit: Patients who are not living with HIV or those who are not on antiretroviral therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in eliminating the HIV reservoir, potentially paving the way for a cure for HIV.
How similar studies have performed: While research on HIV reservoirs is ongoing, this specific approach using phylodynamic modeling is relatively novel and has not been extensively tested.
Where this research is happening
Seattle, United States
- Fred Hutchinson Cancer Center — Seattle, United States (Active)
Researchers
- Principal investigator: Reeves, Daniel — Fred Hutchinson Cancer Center
- Study coordinator: Reeves, Daniel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.