Understanding How HIV Particles Form
HIV particle morphology and biogenesis
This project looks at how the HIV virus builds itself, which helps us find new ways to fight the infection.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-11128698 on NIH RePORTER |
What this research studies
We want to learn more about how the human immunodeficiency virus (HIV) makes copies of itself inside the body. Specifically, we are focusing on how new HIV particles are put together, a process called virus assembly. By studying the tiny building blocks and steps involved, we hope to uncover new weaknesses in the virus. This deeper understanding could lead to new medicines or even a cure for HIV.
Who could benefit from this research
Good fit: Patients living with HIV could ultimately benefit from the new treatments that may arise from this fundamental understanding of the virus.
Not a fit: Patients without HIV would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could identify new targets for antiretroviral drugs and advance therapies for HIV.
How similar studies have performed: While related studies on other retroviruses have provided insights, the detailed assembly process of HIV-1 particles remains largely unexplored.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Mansky, Louis M — University of Minnesota
- Study coordinator: Mansky, Louis M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.