Understanding how HIV interacts with the immune system
CHEETAH Center for the Structural Biology of HIV Infection, Restriction, and Viral Dynamics
This study is exploring new ways to see how HIV interacts with the immune system, using advanced imaging techniques to help us understand the virus better, which could lead to improved treatments for people living with HIV.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project ID | NIH-11076754 on NIH RePORTER |
What this research studies
This research focuses on developing advanced imaging techniques to study the interactions between HIV and the host immune system. It utilizes state-of-the-art methods such as fluorescence spectroscopy and electron cryotomography to visualize and measure the behavior of HIV in real-time. By creating synthetic antigen binders, the research aims to enhance the understanding of HIV's structure and dynamics, which could lead to better therapeutic strategies. The project involves collaboration among various experts to provide comprehensive insights into HIV biology.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV or those at high risk of HIV infection.
Not a fit: Patients who are not infected with HIV or do not have risk factors for HIV may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and strategies for managing HIV infection.
How similar studies have performed: Previous research has shown success in using advanced imaging techniques to study viral infections, indicating a promising approach in this area.
Where this research is happening
Salt Lake City, United States
- University of Utah — Salt Lake City, United States (Active)
Researchers
- Principal investigator: Puglisi, Joseph D — University of Utah
- Study coordinator: Puglisi, Joseph D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.