Understanding how HIV interacts with the body's antiviral processes
New insights into the interplay between HIV and the autophagy machinery
This study is looking at how HIV tricks our body's natural defense system, called autophagy, to keep itself alive, and it hopes to find new ways to improve treatments for people living with HIV.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-10861886 on NIH RePORTER |
What this research studies
This research investigates the role of autophagy, a cellular process that helps fight infections, in the context of HIV. The researchers aim to understand how HIV manipulates this process to evade the immune system and continue its infection cycle. By exploring the molecular interactions between HIV and autophagy, the study seeks to identify potential new strategies for enhancing HIV treatment and clearance. Patients may benefit from insights that could lead to improved therapies targeting HIV's ability to resist the body's defenses.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who are interested in new treatment options.
Not a fit: Patients who are not infected with HIV or those who have already achieved viral suppression may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance the body's ability to clear HIV infections.
How similar studies have performed: Previous research has shown promise in manipulating autophagy for antiviral purposes, indicating potential for success in this novel approach.
Where this research is happening
Rochester, United States
- University of Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Serra Moreno, Ruth — University of Rochester
- Study coordinator: Serra Moreno, Ruth
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.