Understanding how HIV interacts with substance use disorders using AI
Knowledge discovery and machine learning to elucidate the mechanisms of HIV activity and interaction with substance use disorder
This study is looking at how HIV and substance use can affect thinking and memory, and it's trying to find new ways to help improve brain health for people living with HIV.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of South Carolina at Columbia NIH-funded |
| Lab location | 1 site (Columbia, United States) |
| Project ID | NIH-10890083 on NIH RePORTER |
What this research studies
This research investigates the complex relationship between HIV infection and substance use disorders, particularly focusing on how these factors contribute to cognitive deficits known as HIV-associated neurological disorders (HAND). By utilizing advanced artificial intelligence systems, the project aims to uncover novel interactions and potential therapeutic targets that could improve the quality of life for individuals living with HIV. The research employs literature mining techniques to identify small molecules that may help mitigate the neurological effects of HIV and substance abuse. Patients may benefit from the development of new treatments aimed at alleviating cognitive impairments associated with these conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals living with HIV who also experience cognitive deficits and have a history of substance use.
Not a fit: Patients who do not have HIV or substance use disorders may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that improve cognitive function and overall quality of life for individuals living with HIV and substance use disorders.
How similar studies have performed: Previous research has shown promise in using AI to identify therapeutic targets in complex diseases, suggesting that this approach may yield valuable insights.
Where this research is happening
Columbia, United States
- University of South Carolina at Columbia — Columbia, United States (Active)
Researchers
- Principal investigator: Shtutman, Michael — University of South Carolina at Columbia
- Study coordinator: Shtutman, Michael
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.