Understanding how HIV infects cells and replicates
CHEETAH Center for the Structural Biology of HIV Infection, Restriction, and Viral Dynamics
['FUNDING_OTHER'] · UNIVERSITY OF UTAH · NIH-11076761
This study is looking at how HIV-1 gets into human cells and mixes its genetic material with ours, which could help us find new ways to treat the virus and improve care for people living with HIV.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF UTAH (nih funded) |
| Locations | 1 site (SALT LAKE CITY, UNITED STATES) |
| Trial ID | NIH-11076761 on ClinicalTrials.gov |
What this research studies
This research investigates the early stages of HIV-1 infection, focusing on how the virus enters human cells and integrates its genetic material into the host's DNA. By examining the structural details of the virus and its interactions with host cells, the research aims to uncover the mechanisms that facilitate infection. The approach includes advanced imaging techniques and molecular studies to visualize the virus's entry and the subsequent steps leading to replication. This detailed understanding could inform the development of new therapeutic strategies to combat HIV.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV or those at high risk of HIV infection.
Not a fit: Patients who are not infected with HIV and do not have risk factors for infection may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments that prevent HIV from effectively infecting cells.
How similar studies have performed: Previous research has shown promising results in understanding HIV mechanisms, suggesting that this approach could yield valuable insights.
Where this research is happening
SALT LAKE CITY, UNITED STATES
- UNIVERSITY OF UTAH — SALT LAKE CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BJORKMAN, PAMELA J — UNIVERSITY OF UTAH
- Study coordinator: BJORKMAN, PAMELA J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Biology of HIV Infection