NIH-funded research NIH-funded research

Understanding how HIV care impacts older adults in the U.S.

Official title: PEARL 2.0: The impact of the Ending the HIV Epidemic initiative and risk factor interventions on the projected multimorbidity burden and healthcare costs for people aging with HIV in the United States

Funded at Johns Hopkins University · NIH-10886848 · Data updated 2026-11-12

This study looks at how different health programs can help older adults living with HIV in the U.S. by improving their health and lowering healthcare costs, so that doctors and policymakers can better support their needs as they age.

More Aging research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionJohns Hopkins University
NIH-funded
Lab location1 site (Baltimore, United States)
Project startSeptember 15, 2023
Project endAugust 31, 2025
Funding year2023
Award (this year)$718,176
NIH project number1R56AG081148-01
Project IDNIH-10886848 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are older adults aged 21 and above who are living with HIV and receiving antiretroviral therapy.

Less likely to help

Patients who are not living with HIV or are under the age of 21 may not receive any benefit from this research.

What this research studies

This research investigates the future healthcare needs of older adults living with HIV in the United States, particularly focusing on how interventions aimed at ending the HIV epidemic will affect their health and healthcare costs. By using a computer simulation model, the study will analyze various scenarios to project the impact of reducing risk factors like smoking and obesity on the health of this population. The goal is to provide valuable insights for healthcare policymakers and providers to better allocate resources and improve care for aging individuals with HIV.

Why it matters

Potential benefit: If successful, this research could lead to improved healthcare strategies that enhance the quality of life and reduce healthcare costs for older adults living with HIV.

How similar studies have gone: Previous research has shown success in using simulation models to project healthcare needs and costs for various populations, indicating that this approach is promising.

Where this research is happening

  • Johns Hopkins University
    Baltimore, United States
    Active

Researchers

  • Principal investigator: Althoff, Keri Nicole — Johns Hopkins University
  • Study coordinator: Althoff, Keri Nicole

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.