Understanding how HIV behaves in different cellular environments

Behavior of HIV in Viral Environments (B-HIVE)

['FUNDING_OTHER'] · SEATTLE CHILDREN'S HOSPITAL · NIH-11067812

The B-HIVE Center is looking into how HIV-1 interacts with different cells in the body to better understand how the virus spreads and causes illness, with a team of experts working together to find answers that could help improve treatment for people living with HIV.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorSEATTLE CHILDREN'S HOSPITAL (nih funded)
Locations1 site (SEATTLE, UNITED STATES)
Trial IDNIH-11067812 on ClinicalTrials.gov

What this research studies

The B-HIVE Center focuses on studying the interactions between HIV-1 and cellular factors within various environments that influence the virus's replication cycle. By examining how HIV's limited RNA genome allows for different functions in distinct cellular contexts, researchers aim to uncover the mechanisms that drive HIV pathogenesis and disease progression. This collaborative effort involves experts in multiple scientific fields, including virology and biophysics, to tackle complex questions about HIV behavior during infection.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living with HIV/AIDS who are interested in understanding the biological mechanisms of their condition.

Not a fit: Patients who are not infected with HIV or those who have already achieved long-term viral suppression may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for treating and managing HIV/AIDS.

How similar studies have performed: Previous research has shown promise in understanding viral behavior in cellular environments, suggesting that this approach could yield valuable insights.

Where this research is happening

SEATTLE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome, Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.