Understanding how HIV and COVID-19 affect nerve pain and brain function
Imaging neuroglial mechanisms of neuropathic pain-opioid interaction in HIV
This study is looking at how HIV and COVID-19 might affect nerve pain and brain health, especially for people living with HIV who are recovering from COVID-19, to better understand the causes of their ongoing symptoms.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10553020 on NIH RePORTER |
What this research studies
This research investigates the interactions between HIV and COVID-19, particularly focusing on how these conditions may lead to nerve pain and neurological issues. Using advanced imaging techniques like MRI and spectroscopy, the study aims to identify neuroglial mechanisms that contribute to prolonged symptoms in individuals recovering from COVID-19, especially those living with HIV. By analyzing brain function and inflammation, the research seeks to uncover the biological underpinnings of cognitive disorders and pain experienced by these patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who have experienced neurological symptoms following COVID-19 infection.
Not a fit: Patients who do not have HIV or have not experienced neurological symptoms related to COVID-19 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for patients suffering from neurological complications related to HIV and COVID-19.
How similar studies have performed: Other research has shown promising results in understanding the neurological impacts of COVID-19, but the specific interaction with HIV in this context is still being explored.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Loggia, Marco Luciano — Massachusetts General Hospital
- Study coordinator: Loggia, Marco Luciano
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.