Understanding how HIV and cocaine abuse interact biologically.
Gene Network Identification and Integration (GNetii) Approach to Understanding the Biology Underlying HIV and Drug Abuse.
This study is looking at how cocaine use affects HIV in people living with the virus, especially how it might make the virus harder to control, so we can find better ways to help those who are dealing with both HIV and drug use.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Research Triangle Institute NIH-funded |
| Lab location | 1 site (Research Triangle Park, United States) |
| Project ID | NIH-10868765 on NIH RePORTER |
What this research studies
This research aims to explore the biological networks that influence HIV viral load and latent reservoirs in individuals living with HIV, particularly focusing on the impact of cocaine abuse. By analyzing genetic factors and their regulation, the study seeks to uncover how cocaine may exacerbate HIV progression and complicate treatment efforts. The approach involves integrating large datasets to provide a comprehensive view of the interactions between HIV and drug abuse, which could lead to improved management strategies for affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are HIV-positive individuals who also use cocaine.
Not a fit: Patients who are HIV-negative or do not use cocaine are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better treatment strategies for HIV-positive individuals who also struggle with cocaine addiction.
How similar studies have performed: Previous research has shown that integrative approaches to understanding HIV biology can yield significant insights, suggesting that this study's methodology is promising.
Where this research is happening
Research Triangle Park, United States
- Research Triangle Institute — Research Triangle Park, United States (Active)
Researchers
- Principal investigator: Johnson, Eric Otto — Research Triangle Institute
- Study coordinator: Johnson, Eric Otto
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.