Understanding how HIV affects walking and balance in older adults
Central Control and Neuroinflammatory Mechanisms of Locomotion in Older Adults with HIV
This study is looking at how HIV affects walking and balance in older adults aged 50 and up, and it aims to find ways to help improve their mobility and reduce the risk of falls.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albert Einstein College of Medicine NIH-funded |
| Lab location | 1 site (Bronx, United States) |
| Project ID | NIH-10990499 on NIH RePORTER |
What this research studies
This research investigates the impact of HIV on mobility and gait disorders in older adults, particularly those aged 50 and above. It focuses on how neuroinflammation and disruptions in brain circuitry may contribute to these mobility impairments. By using advanced imaging techniques and a dual-task walking paradigm, the study aims to assess brain activation during walking and identify potential interventions to improve walking performance and reduce fall risk. Participants will include older adults with HIV and a control group without HIV.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 50 and above who are living with HIV.
Not a fit: Patients under the age of 50 or those without HIV may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for enhancing mobility and reducing fall risk in older adults living with HIV.
How similar studies have performed: Previous research has shown promising results in understanding mobility impairments in older adults, but this specific focus on HIV-related neuroinflammation is relatively novel.
Where this research is happening
Bronx, United States
- Albert Einstein College of Medicine — Bronx, United States (Active)
Researchers
- Principal investigator: Holtzer, Roee — Albert Einstein College of Medicine
- Study coordinator: Holtzer, Roee
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.