Understanding how HIV affects social brain health
Official title: Evaluating Social Brain Health in HIV: An RDoC-based approach
Funded at University of Alabama at Birmingham · NIH-11100113 · Data updated 2026-11-12
This study looks at how HIV affects the way people understand social situations and emotions, focusing on certain parts of the brain that help with these skills, to better understand the social challenges faced by those living with HIV.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project start | March 1, 2025 |
| Project end | January 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $733,355 |
| NIH project number | 1R01MH139613-01 |
| Project ID | NIH-11100113 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with HIV who experience challenges in social interactions.
✕Less likely to help
Patients who do not have HIV or those who do not experience social cognition difficulties may not benefit from this research.
What this research studies
This research investigates the impact of HIV on social cognition, which includes the ability to recognize social cues and understand others' emotions and intentions. By examining specific brain regions associated with social functioning, such as the amygdala and prefrontal cortex, the study aims to identify how difficulties in these areas can affect daily social interactions for individuals living with HIV. The research employs a multi-level assessment approach, integrating neural and behavioral evaluations to gain insights into the mechanisms that contribute to social challenges faced by patients. Ultimately, the goal is to enhance understanding of social brain health in the context of HIV.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for enhancing social functioning and support for individuals living with HIV.
How similar studies have gone: Previous research has shown promising results in understanding social cognition in various neurological conditions, suggesting that this approach could yield valuable insights for HIV as well.
Where this research is happening
-
University of Alabama at Birmingham
Birmingham, United States Active
Researchers
- Principal investigator: Lee, Junghee — University of Alabama at Birmingham
- Study coordinator: Lee, Junghee
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.