Understanding how HIV affects lung blood vessels
Novel mechanisms of HIV-associated pulmonary vascular disease
This study is looking at how HIV affects lung and heart health by examining how certain proteins from the virus change blood vessels in the lungs, especially as people get older, to help improve care for those living with HIV.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Augusta University NIH-funded |
| Lab location | 1 site (Augusta, United States) |
| Project ID | NIH-11171664 on NIH RePORTER |
What this research studies
This research investigates the impact of HIV on pulmonary vascular disease (PVD), a serious complication affecting the lungs and heart in people living with HIV. The study aims to identify how certain proteins from the HIV virus contribute to changes in blood vessels in the lungs, particularly as individuals age. Using mouse models, researchers will explore the mechanisms behind these changes and how they relate to the overall health of the cardiovascular system. The findings could lead to new insights into managing heart and lung health in HIV patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV, particularly those experiencing cardiovascular issues or aging-related complications.
Not a fit: Patients who are not living with HIV or do not have cardiovascular complications may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for pulmonary vascular disease in individuals living with HIV.
How similar studies have performed: Previous research has shown promising results in understanding HIV-related complications, but this specific approach to pulmonary vascular disease is relatively novel.
Where this research is happening
Augusta, United States
- Augusta University — Augusta, United States (Active)
Researchers
- Principal investigator: Belin de Chantemele, Eric J — Augusta University
- Study coordinator: Belin de Chantemele, Eric J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.