Understanding how HIV affects children's immune systems
Project-001
['FUNDING_P01'] · EMORY UNIVERSITY · NIH-11060881
This study is looking at how the immune system works with HIV in children to understand why their bodies respond differently than adults, with the hope of finding new ways to help treat and possibly cure HIV in young patients.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | EMORY UNIVERSITY (nih funded) |
| Locations | 1 site (ATLANTA, UNITED STATES) |
| Trial ID | NIH-11060881 on ClinicalTrials.gov |
What this research studies
This research aims to explore the interactions between the immune system and HIV in children, focusing on how HIV reservoirs are formed and maintained in young patients. By studying the roles of specific immune factors like IL-10 and TGF-β, the project seeks to uncover why children living with HIV have different immune responses compared to adults. The research will involve analyzing immune cells from infants and children to identify potential new strategies for curing HIV in this population. The ultimate goal is to develop targeted treatments that can effectively address the unique challenges faced by children with HIV.
Who could benefit from this research
Good fit: Ideal candidates for this research include children living with HIV, particularly those under the age of 20.
Not a fit: Patients who are not living with HIV or those who are adults may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatment strategies that effectively reduce or eliminate HIV reservoirs in children, improving their long-term health outcomes.
How similar studies have performed: Previous research has shown promise in understanding immune responses in HIV, but this specific approach targeting the pediatric population is relatively novel.
Where this research is happening
ATLANTA, UNITED STATES
- EMORY UNIVERSITY — ATLANTA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHAHROUDI, ANN M — EMORY UNIVERSITY
- Study coordinator: CHAHROUDI, ANN M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus