Understanding how HIV affects brain metabolism
Evaluating Changes to the Metabolic Profile of the Central Nervous System due to Active NeuroHIV Infection
This study looks at how HIV affects the way the brain processes fats and other important substances, and how treatment with antiretroviral therapy might change that, all to help improve care for people living with HIV who may have brain-related issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11199947 on NIH RePORTER |
What this research studies
This research investigates the metabolic changes in the brain caused by HIV infection and the effects of antiretroviral therapy. It focuses on how HIV alters lipid metabolism, which is crucial for brain function, and aims to identify larger metabolites that have not been thoroughly studied before. By analyzing brain samples from individuals living with HIV, the research seeks to provide a comprehensive understanding of how these metabolic changes contribute to neurological impairments. This could lead to better management strategies for patients affected by HIV.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who are undergoing antiretroviral therapy.
Not a fit: Patients who are not living with HIV or those who do not have neurological impairments related to HIV may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies that mitigate neurological impairments in individuals living with HIV.
How similar studies have performed: While there has been some research on small metabolites in HIV-infected individuals, this study's focus on larger metabolites and lipid metabolism is relatively novel.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: White, Cory Justin — Emory University
- Study coordinator: White, Cory Justin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.