Understanding how HIV affects brain metabolism
Evaluating Changes to the Metabolic Profile of the Central Nervous System due to Active NeuroHIV Infection
This study is looking at how HIV affects the way the brain uses fats for energy and how it responds to changes in diet, which could help us understand the links between HIV, brain health, and mood issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11074963 on NIH RePORTER |
What this research studies
This research investigates how active NeuroHIV infection alters the metabolic profile of the central nervous system, particularly focusing on lipid metabolism in the brain. It aims to explore the brain's use of lipids for energy and how it adapts to dietary changes that affect lipid availability. By utilizing advanced mouse models, the study examines the role of specific enzymes linked to mood disorders and their impact on brain function. This research could provide insights into the connections between HIV, neurological diseases, and mood disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals living with HIV who are experiencing neurological symptoms or mood disorders.
Not a fit: Patients without HIV or those not experiencing neurological or mood-related issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for neurological and mood disorders associated with HIV infection.
How similar studies have performed: Previous research has shown promising results in understanding lipid metabolism in the brain, but this specific approach to studying NeuroHIV's effects is relatively novel.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: White, Cory Justin — Emory University
- Study coordinator: White, Cory Justin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.