Understanding how HIV affects blood pressure and heart health
Official title: Mechanisms of HIV-associated Hypertension
Funded at Augusta University · NIH-10945172 · Data updated 2026-11-12
This study is looking at how HIV might cause high blood pressure and heart problems in people living with the virus, using mice to understand how certain proteins and inflammation affect blood vessels, with the goal of finding new ways to help improve heart health for those with HIV.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Augusta University NIH-funded |
| Lab location | 1 site (Augusta, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $641,960 |
| NIH project number | 1R01HL175471-01 |
| Project ID | NIH-10945172 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals living with HIV who are experiencing hypertension or are at risk for cardiovascular disease.
✕Less likely to help
Patients who do not have HIV or those without hypertension may not benefit from this research.
What this research studies
This research investigates the mechanisms by which HIV may contribute to high blood pressure and cardiovascular disease in individuals living with HIV. It focuses on the role of HIV-derived proteins and inflammation in causing vascular dysfunction and sympatho-activation, which can lead to hypertension. The study utilizes a mouse model to explore these mechanisms and aims to identify potential therapeutic targets to improve cardiovascular health in people with HIV.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that help manage hypertension and reduce cardiovascular disease risk in people living with HIV.
How similar studies have gone: Previous research has shown that understanding the relationship between HIV and cardiovascular health can lead to significant advancements in treatment strategies, indicating that this approach has potential for success.
Where this research is happening
-
Augusta University
Augusta, United States Active
Researchers
- Principal investigator: Belin de Chantemele, Eric J — Augusta University
- Study coordinator: Belin de Chantemele, Eric J
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.