Understanding how HIV-1 matures and assembles
Project 1. Maturation and Assembly
This study is looking at how the HIV-1 virus grows and puts itself together, with the goal of finding new ways to create medicines that can help people living with HIV.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-11078370 on NIH RePORTER |
What this research studies
This research focuses on identifying critical interactions and complexes involved in the maturation and assembly of the HIV-1 virus. By studying the viral components and their interactions, the project aims to uncover potential targets for new antiviral drugs. The research employs advanced techniques such as NMR, CryoEM, and computational methods to analyze the molecular structures and mechanisms at play. Patients may benefit from the development of novel inhibitors that could enhance treatment options for HIV-1.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV-1 who may benefit from new treatment options.
Not a fit: Patients who are not infected with HIV-1 or those with other unrelated health conditions may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective antiviral therapies for HIV-1.
How similar studies have performed: Previous research has shown promise in targeting similar viral assembly processes, indicating potential for success in this area.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Ganser-Pornillos, Barbie K. — University of Pittsburgh at Pittsburgh
- Study coordinator: Ganser-Pornillos, Barbie K.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.