Understanding how herpes virus proteins help form infectious virus particles
Elucidation of genetic networks of HSV-1 virion proteins and discovery of their functions in the morphogenesis of the infectious virus particle
This study is looking at how certain proteins made by the herpes simplex virus help the virus spread and cause illness, with the hope that understanding this could lead to better treatments for people dealing with HSV infections.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10553596 on NIH RePORTER |
What this research studies
This research investigates the genetic networks of proteins produced by the herpes simplex virus (HSV-1) and their roles in the formation of infectious virus particles. By studying the structure and function of these proteins, the research aims to uncover how they contribute to the virus's ability to replicate and cause disease. Patients may benefit from this research as it could lead to new treatments for HSV infections, which can cause serious health issues like blindness and encephalitis.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have been diagnosed with HSV-1 or are at risk of HSV-related complications, such as ocular disease or encephalitis.
Not a fit: Patients who do not have HSV infections or related complications may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective treatments for herpes virus infections.
How similar studies have performed: Previous research has shown promise in understanding viral proteins and their roles in infection, suggesting that this approach could yield valuable insights.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Desai, Prashant J — Johns Hopkins University
- Study coordinator: Desai, Prashant J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.