Understanding how hepatitis C virus causes chronic infections
Viral Determinants of Chronic Hepacivirus Infection
This study is looking at how the hepatitis C virus can stick around in the body for a long time and avoid the immune system, using a rodent model to find ways to improve treatments for people living with hepatitis C.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Research Inst Nationwide Children's Hosp NIH-funded |
| Lab location | 1 site (Columbus, United States) |
| Project ID | NIH-11097259 on NIH RePORTER |
What this research studies
This research investigates the hepatitis C virus (HCV) and its ability to create long-lasting chronic infections in individuals. By studying the genetic and molecular properties of HCV, the research aims to identify specific regions of the virus that help it evade the immune system. The project utilizes a rodent model to better understand how HCV persists and causes disease, which could lead to improved treatments. Patients may benefit from insights gained about HCV's mechanisms of infection and persistence.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with chronic hepatitis C infections.
Not a fit: Patients who do not have hepatitis C or those with acute infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating chronic hepatitis C infections.
How similar studies have performed: Previous research has shown promise in understanding chronic viral infections, but this specific approach using a rodent model is relatively novel.
Where this research is happening
Columbus, United States
- Research Inst Nationwide Children's Hosp — Columbus, United States (Active)
Researchers
- Principal investigator: Kapoor, Amit — Research Inst Nationwide Children's Hosp
- Study coordinator: Kapoor, Amit
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.