Understanding how heme signaling affects aging and lifespan
Lifespan Regulation by Inter-Organellar Heme Signaling
['FUNDING_R01'] · GEORGIA INSTITUTE OF TECHNOLOGY · NIH-10894272
This study is looking at how a special molecule called heme affects aging and how long we live, using tiny organisms like yeast and worms to understand how changes in heme levels can influence our health as we get older.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | GEORGIA INSTITUTE OF TECHNOLOGY (nih funded) |
| Locations | 1 site (ATLANTA, UNITED STATES) |
| Trial ID | NIH-10894272 on ClinicalTrials.gov |
What this research studies
This research investigates the role of heme, a vital molecule in cells, in regulating aging and lifespan. It aims to uncover how changes in heme levels influence metabolic processes associated with aging, using advanced techniques like genetically encoded sensors and mass spectrometry. By studying model organisms such as yeast and worms, the research seeks to identify the mechanisms through which heme signaling operates and its impact on cellular health and longevity.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals interested in the biological mechanisms of aging and those with age-related health concerns.
Not a fit: Patients with acute or non-age-related conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for promoting healthy aging and extending lifespan.
How similar studies have performed: Previous studies have shown promising results in extending lifespan through heme regulation in model organisms, indicating potential for success in this area.
Where this research is happening
ATLANTA, UNITED STATES
- GEORGIA INSTITUTE OF TECHNOLOGY — ATLANTA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: REDDI, AMIT RAM — GEORGIA INSTITUTE OF TECHNOLOGY
- Study coordinator: REDDI, AMIT RAM
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.