Understanding how heart structure and function differences affect arrhythmias
Modelling structural and functional heterogeneity in heart failure reveals arrhythmic impact
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA AT DAVIS · NIH-10449125
This study is looking at how changes in the heart's structure and function can lead to irregular heartbeats, especially in people with heart failure, to find new ways to treat these conditions and help improve heart health.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA AT DAVIS (nih funded) |
| Locations | 1 site (DAVIS, UNITED STATES) |
| Trial ID | NIH-10449125 on ClinicalTrials.gov |
What this research studies
This research investigates the complex mechanisms behind heart arrhythmias by using advanced computational modeling techniques. It aims to analyze how variations in heart structure and function contribute to dangerous heart rhythms, particularly in patients with heart failure. By studying calcium dynamics and cellular interactions at multiple scales, the research seeks to identify potential targets for new antiarrhythmic therapies. Patients may benefit from insights that could lead to improved treatments and management strategies for arrhythmias.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with heart failure or those experiencing arrhythmias.
Not a fit: Patients without any history of heart conditions or arrhythmias may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective treatments for heart arrhythmias, improving patient outcomes.
How similar studies have performed: Previous research has shown promise in using computational modeling to understand arrhythmias, suggesting that this approach could yield valuable insights.
Where this research is happening
DAVIS, UNITED STATES
- UNIVERSITY OF CALIFORNIA AT DAVIS — DAVIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SATO, DAISUKE — UNIVERSITY OF CALIFORNIA AT DAVIS
- Study coordinator: SATO, DAISUKE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.