NIH-funded research R21 grant

Understanding how heart signals affect feelings from alcohol consumption

Official title: The role of peripheral cardiovascular signals in the interoceptive effects of alcohol

Funded at Univ of North Carolina Chapel Hill · NIH-10592619 · Data updated 2026-11-12

This study looks at how your heart rate and blood pressure affect how you feel when you drink alcohol, helping us understand why different amounts of alcohol can make you feel lightheaded or relaxed.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startAugust 1, 2023
Project endJuly 31, 2025
Funding year2023
Award (this year)$391,393
NIH project number1R21AA030093-01A1
Project IDNIH-10592619 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults who consume alcohol and are interested in understanding its effects on their body and behavior.

Less likely to help

Patients who do not consume alcohol or have contraindications to alcohol use may not benefit from this research.

What this research studies

This research investigates how signals from the cardiovascular system, such as heart rate and blood pressure, influence the feelings and sensations experienced when consuming alcohol. By examining these interoceptive effects, the study aims to understand how different doses of alcohol can lead to varying sensations like lightheadedness or relaxation. The research will involve measuring these cardiovascular signals in participants as they consume alcohol to see how they relate to their experiences. This could help in understanding the behavioral impacts of alcohol consumption.

Why it matters

Potential benefit: If successful, this research could lead to better strategies for managing alcohol consumption and its effects on behavior.

How similar studies have gone: While there has been some research on the central nervous system's role in alcohol effects, the specific focus on cardiovascular signals in this context is relatively novel.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Besheer, Joyce — Univ of North Carolina Chapel Hill
  • Study coordinator: Besheer, Joyce

Related research

Other NIH-funded projects on the same topics.

  • A center for coordinating data related to heart and blood health.

    This study is working on a new system to gather and analyze health information about heart and blood disorders, which could lead to better ways to diagnose and treat these conditions, ultimately helping patients like you.

    NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-9732880

  • Healthy work design and worker well-being

    A multi-site program aims to improve the health and well-being of workers by studying how work design affects safety, stress, and quality of life.

    NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11631666

  • Unified and fair multimodal learning for autoimmune diseases

    A patient-friendly AI approach will combine many kinds of health data to improve diagnosis and personalized care for autoimmune diseases, including lupus.

    NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11625649

  • Structural factors linking minimum wage, COVID-19, and community violence

    A long-term study will explore whether higher minimum wages and pandemic-related economic factors are connected to changes in violence in US communities.

    NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11624218

  • Non-invasive tears biomarker for early Alzheimer's in LMICs

    A low-cost, tear-based biomarker approach aims to detect early Alzheimer’s disease in older adults in Peru and similar settings.

    NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11623923

  • How HPV interacts with our cells' DNA damage system and its effect on cancer

    This project looks at how high-risk HPV uses the body’s DNA repair machinery to replicate and potentially drive cancer, with the goal of finding new antiviral and cancer-fighting approaches for people affected by HPV-related diseases.

    NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11622604

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.