Understanding how heart cells move to form the heart structure
Investigating collective myocardial cell movement during heart tube formation
This study is looking at how heart cells move and work together to form the early heart structure, which could help us understand heart development better, and it's being done by students and researchers at the University of Mississippi.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Mississippi NIH-funded |
| Lab location | 1 site (University, United States) |
| Project ID | NIH-10439340 on NIH RePORTER |
What this research studies
This research investigates the collective movement of heart cells during the early stages of heart development, specifically focusing on how these cells migrate to form the primitive heart tube. By examining the interactions between different cell types and the signals that guide this movement, the study aims to uncover the molecular mechanisms involved in heart formation. The research employs a multi-dimensional approach, utilizing genetic analysis and various model organisms like zebrafish and mice to explore these processes at cellular and molecular levels. This work is being conducted by students and researchers at the University of Mississippi.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with congenital heart defects or those at risk of developing such conditions.
Not a fit: Patients with acquired heart conditions unrelated to congenital defects may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a better understanding of congenital heart defects and potentially inform new therapeutic strategies for their prevention or treatment.
How similar studies have performed: Previous research has shown success in understanding heart development through similar genetic and cellular approaches, indicating that this study builds on established knowledge.
Where this research is happening
University, United States
- University of Mississippi — University, United States (Active)
Researchers
- Principal investigator: Bloomekatz, Joshua Eli — University of Mississippi
- Study coordinator: Bloomekatz, Joshua Eli
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.