NIH-funded research R01 grant

Understanding how heart and metabolic health affects spine strength over time

Official title: Evaluating the Association between Cardiometabolic Health Over the Lifespan and Vertebral Strength

Funded at Tulane University of Louisiana · NIH-11232991 · Data updated 2026-11-12

This study is looking at how conditions like high blood pressure and diabetes affect the strength of bones in older adults, helping us understand if these health issues make bones weaker and increase the risk of fractures over time.

More Cardiometabolic Health research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionTulane University of Louisiana
NIH-funded
Lab location1 site (New Orleans, United States)
Project startNovember 16, 2024
Project endFebruary 28, 2028
Funding year2024
Award (this year)$526,272
NIH project number7R01AR080868-03
Project IDNIH-11232991 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are older adults with one or more cardiometabolic conditions.

Less likely to help

Patients without any cardiometabolic conditions or those who are not older adults may not benefit from this research.

What this research studies

This research investigates the relationship between cardiometabolic health conditions, such as hypertension and diabetes, and the strength of vertebrae in older adults. By examining a large group of participants over several years, the study aims to understand how these health issues impact bone density and the risk of fractures. Advanced imaging techniques will be used to measure bone strength, providing insights into how multiple cardiometabolic conditions interact and affect vertebral health. This longitudinal approach will help clarify the long-term effects of cardiometabolic disorders on bone health.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing vertebral fractures in older adults by addressing cardiometabolic health.

How similar studies have gone: Previous research has shown that understanding the interplay between cardiometabolic health and bone strength can lead to significant advancements in fracture prevention strategies.

Where this research is happening

  • Tulane University of Louisiana
    New Orleans, United States
    Active

Researchers

  • Principal investigator: Wright, Nicole C — Tulane University of Louisiana
  • Study coordinator: Wright, Nicole C

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.