Understanding how hair follicles grow and maintain their size
Tissue Size and Precision Control in Growing Hair Follicles
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA-IRVINE · NIH-10993160
This study looks at how hair follicles grow and communicate with each other by using special mice that grow really long hair, and it aims to help us understand how different cells work together to control hair growth.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA-IRVINE (nih funded) |
| Locations | 1 site (IRVINE, UNITED STATES) |
| Trial ID | NIH-10993160 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms by which hair follicles achieve their intended sizes and how they communicate over large distances within biological tissues. By studying mutant mice that grow unusually long hair, the researchers aim to uncover the roles of different cell types and their interactions in regulating hair growth. The approach combines mathematical modeling with experimental techniques, including single-cell RNA sequencing, to explore how signals are transmitted between stem cells and their progeny. This could lead to insights into the fundamental processes of tissue growth and maintenance.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals experiencing hair loss or related hair growth disorders.
Not a fit: Patients with conditions unrelated to hair growth or tissue size regulation may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for hair loss and other conditions related to tissue growth.
How similar studies have performed: Other research has shown promise in understanding tissue growth and signaling, but this specific approach is relatively novel.
Where this research is happening
IRVINE, UNITED STATES
- UNIVERSITY OF CALIFORNIA-IRVINE — IRVINE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PLIKUS, MAKSIM V — UNIVERSITY OF CALIFORNIA-IRVINE
- Study coordinator: PLIKUS, MAKSIM V
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.