Understanding how gut signals affect brain function and metabolism
Gut-brain axis in metabolic disease
['FUNDING_P01'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-10667314
This study is looking at how signals from your gut affect your brain and can influence things like how much you eat and your weight, with the hope of finding new, less invasive treatments for obesity.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded) |
| Locations | 1 site (ANN ARBOR, UNITED STATES) |
| Trial ID | NIH-10667314 on ClinicalTrials.gov |
What this research studies
This research investigates the connection between gut signals and brain function, particularly how these signals influence food intake, body weight, and glucose metabolism. By examining the gut-brain axis, the research aims to uncover mechanisms that could lead to new treatments for obesity that are less invasive than current surgical options. The project will utilize advanced techniques to trace neural pathways and understand how gut-derived signals interact with brain circuitry. This comprehensive approach seeks to enhance our understanding of metabolic regulation and develop innovative therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals struggling with obesity and related metabolic disorders.
Not a fit: Patients who are not overweight or do not have metabolic disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new, effective treatments for obesity that do not require invasive surgery.
How similar studies have performed: Previous research has shown promising results in understanding the gut-brain axis, suggesting that this approach could lead to significant advancements in obesity treatment.
Where this research is happening
ANN ARBOR, UNITED STATES
- UNIVERSITY OF MICHIGAN AT ANN ARBOR — ANN ARBOR, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SEELEY, RANDY J — UNIVERSITY OF MICHIGAN AT ANN ARBOR
- Study coordinator: SEELEY, RANDY J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.