Understanding how gut microbes respond to drugs and inflammation
Official title: From here to eternity: gut microbial response to drug therapy and inflammation
Funded at Northern California Institute/res/edu · NIH-10915513 · Data updated 2026-11-12
This study is looking at how the tiny microbes in our gut react to medications and inflammation, with the hope of finding better ways to treat inflammatory diseases that could help patients feel better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northern California Institute/res/edu NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $383,250 |
| NIH project number | 5R35GM151349-02 |
| Project ID | NIH-10915513 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with inflammatory diseases who are undergoing drug therapy.
✕Less likely to help
Patients without inflammatory conditions or those not receiving drug therapy may not benefit from this research.
What this research studies
This research investigates the role of gut microbes in responding to drug therapies and inflammation. By analyzing microbial genes and pathways, the study aims to uncover how these responses affect overall health and disease outcomes. The approach involves examining the genetic determinants of microbial reactions to various treatments, which could lead to more effective microbiome-targeted therapies. Patients may benefit from insights that could improve treatment strategies for inflammatory diseases.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatments for patients with inflammatory conditions by leveraging the gut microbiome.
How similar studies have gone: Other research has shown promising results in understanding the microbiome's role in health, suggesting that this approach could yield significant insights.
Where this research is happening
-
Northern California Institute/res/edu
San Francisco, United States Active
Researchers
- Principal investigator: Nayak, Renuka Rajendra — Northern California Institute/res/edu
- Study coordinator: Nayak, Renuka Rajendra
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.