Understanding how gut microbes affect cancer treatment responses
Defining novel mechanisms of microbiota in regulating anti-tumor responses
This study is looking at how the bacteria in our gut might affect cancer growth and how well certain treatments work, especially immunotherapies, to help find new ways to improve cancer care for patients like you.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10865828 on NIH RePORTER |
What this research studies
This research investigates the role of gut microbiota in cancer progression and treatment responses, particularly focusing on how these microbes can influence the effectiveness of immunotherapies. By exploring the interactions between the microbiota and the immune system, the study aims to uncover mechanisms that either promote tumor growth or enhance anti-tumor immunity. Patients may benefit from insights that could lead to new strategies for manipulating gut microbes to improve cancer treatment outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are cancer patients undergoing immunotherapy who may benefit from tailored microbiota interventions.
Not a fit: Patients with non-cancerous conditions or those not receiving immunotherapy may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative therapies that enhance the effectiveness of cancer treatments by targeting gut microbiota.
How similar studies have performed: Other research has shown promising results in manipulating microbiota to improve cancer treatment responses, indicating that this approach has potential for success.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Lyu, Mengze — Weill Medical Coll of Cornell Univ
- Study coordinator: Lyu, Mengze
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.