Understanding how gut immune cells interact to manage inflammation and tolerance
Official title: Cell-cell interactions driving gut inflammation and tolerance
Funded at Rockefeller University · NIH-10896417 · Data updated 2026-11-12
This study is looking at how immune cells in the gut work together, which could help us understand why some people have food allergies or gut inflammation, and it might lead to better treatments for these conditions.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rockefeller University NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $139,671 |
| NIH project number | 5K99AI173537-02 |
| Project ID | NIH-10896417 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals suffering from food allergies or inflammatory bowel disease.
✕Less likely to help
Patients with non-gut related immune disorders may not receive direct benefits from this research.
What this research studies
This research investigates the complex interactions between immune cells in the gut, focusing on how these interactions can lead to either tolerance to food and bacteria or inflammation. By utilizing a novel technology called LIPSTIC, the study aims to identify specific dendritic cells and their roles in regulating immune responses. Patients may benefit from insights into how their immune systems react to food and pathogens, potentially leading to new treatments for conditions like food allergies and inflammatory bowel disease.
Why it matters
Potential benefit: If successful, this research could lead to new therapies for managing food allergies and inflammatory bowel diseases.
How similar studies have gone: Other research has shown promise in understanding immune cell interactions, but this specific approach using LIPSTIC technology is relatively novel.
Where this research is happening
-
Rockefeller University
New York, United States Active
Researchers
- Principal investigator: Campos Canesso, Maria Cecilia — Rockefeller University
- Study coordinator: Campos Canesso, Maria Cecilia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.