Understanding how gut health and inflammation affect heart disease in people with HIV

Elucidating the role of the gut reservoir and inflammation in driving cardiovascular disease among persons living with HIV

['FUNDING_R01'] · EMORY UNIVERSITY · NIH-10875277

This study is looking at how gut health and inflammation might affect heart health in people living with HIV, and it invites participants to help researchers understand the links between these factors.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorEMORY UNIVERSITY (nih funded)
Locations1 site (ATLANTA, UNITED STATES)
Trial IDNIH-10875277 on ClinicalTrials.gov

What this research studies

This research investigates the connection between gut health, inflammation, and cardiovascular disease (CVD) in individuals living with HIV. It focuses on how chronic inflammation, often seen in these patients, increases their risk of heart-related issues. By utilizing advanced techniques like multi-OMICS approaches, the study aims to identify specific biological pathways that contribute to this heightened risk. Patients may be involved in providing samples and data to help uncover these mechanisms.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living with HIV who are on antiretroviral therapy and may be experiencing cardiovascular issues.

Not a fit: Patients who are HIV-negative or those not on antiretroviral therapy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing cardiovascular disease in people living with HIV.

How similar studies have performed: Previous research has shown promising results in understanding the links between inflammation and cardiovascular disease in HIV-positive populations, suggesting that this approach could yield valuable insights.

Where this research is happening

ATLANTA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome, Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.