Understanding how gut health affects brain function in Parkinson's disease
A Consortium for Gut-Brain Communication in Parkinson's Disease
['FUNDING_U01'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-10987474
This study is looking at how gut health affects brain function in people with Parkinson's disease, and it's for anyone with Parkinson's, whether they have tummy issues or not, as well as healthy individuals to help us learn more about this connection.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS GENERAL HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10987474 on ClinicalTrials.gov |
What this research studies
This research investigates the connection between gut health and brain function in individuals with Parkinson's disease. It involves collecting data from patients with varying stages of Parkinson's, including those with and without gastrointestinal symptoms, as well as healthy controls. Participants will undergo detailed assessments of their Parkinson's symptoms and gastrointestinal function, and some will participate in brain imaging studies to explore how meals affect gut-brain communication. The goal is to better understand how gut motility and brain function are related in Parkinson's disease.
Who could benefit from this research
Good fit: Ideal candidates include individuals diagnosed with Parkinson's disease, regardless of whether they experience gastrointestinal symptoms, as well as age and sex-matched healthy controls.
Not a fit: Patients with Parkinson's disease who are not willing or able to participate in detailed assessments or imaging studies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and management strategies for patients with Parkinson's disease by addressing gut-related symptoms.
How similar studies have performed: Previous research has shown promising results in understanding gut-brain interactions in other neurological conditions, suggesting potential for success in this novel approach.
Where this research is happening
BOSTON, UNITED STATES
- MASSACHUSETTS GENERAL HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KUO, BRADEN — MASSACHUSETTS GENERAL HOSPITAL
- Study coordinator: KUO, BRADEN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.