Understanding how gut bacteria interact with mucus in the digestive system
Official title: Exploring the complex interactions between gut microbes and mucus
Funded at Medical University of South Carolina · NIH-10941609 · Data updated 2026-11-12
This study is looking at how the bacteria in your gut interact with the protective mucus lining your digestive system, which could help us understand gut health better and find new ways to treat related issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Medical University of South Carolina NIH-funded |
| Lab location | 1 site (Charleston, United States) |
| Project start | September 1, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $377,500 |
| NIH project number | 1R35GM155451-01 |
| Project ID | NIH-10941609 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with gastrointestinal disorders or those interested in gut health.
✕Less likely to help
Patients with no gastrointestinal issues or those not interested in gut microbiome research may not benefit from this research.
What this research studies
This research investigates the complex relationships between gut bacteria and mucus, which is a protective layer in the gastrointestinal tract. It aims to uncover how these bacteria interact with mucus, how they influence its production, and how mucus affects bacterial behavior. By utilizing advanced techniques and collaborative expertise, the study seeks to clarify the roles of mucus in maintaining gut health and its impact on bacterial communities. This knowledge could lead to better understanding of gut health and potential treatments for related disorders.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for gastrointestinal disorders by enhancing our understanding of gut health.
How similar studies have gone: Other research has shown promising results in understanding gut microbiome interactions, indicating that this approach has potential for success.
Where this research is happening
-
Medical University of South Carolina
Charleston, United States Active
Researchers
- Principal investigator: Engevik, Melinda Anne — Medical University of South Carolina
- Study coordinator: Engevik, Melinda Anne
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.