Understanding how gut bacteria influence immune responses after a stroke
The Role of Dendritic Cells in Regulating the Gut-Brain Immune Axis in Ischemic Stroke
['FUNDING_R01'] · WEILL MEDICAL COLL OF CORNELL UNIV · NIH-11035216
This study is looking at how certain immune cells and gut bacteria work together after a stroke to affect healing and inflammation, with the hope of finding new ways to help stroke patients recover better.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WEILL MEDICAL COLL OF CORNELL UNIV (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11035216 on ClinicalTrials.gov |
What this research studies
This research investigates the role of dendritic cells and gut microbiota in regulating immune responses following ischemic stroke. By examining how these factors contribute to inflammation and tissue injury, the study aims to uncover new therapeutic strategies for stroke patients. The approach includes analyzing the interactions between gut bacteria and immune cells to better understand their impact on recovery after a stroke. Patients may benefit from insights that could lead to innovative treatments targeting immune modulation.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced an ischemic stroke and are interested in potential new treatment options.
Not a fit: Patients who have not had a stroke or those with chronic neurological conditions unrelated to ischemic stroke may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that improve recovery and outcomes for stroke patients by targeting immune responses.
How similar studies have performed: Previous research has shown promising results in understanding the gut-brain axis and its influence on immune responses, suggesting potential for success in this novel approach.
Where this research is happening
NEW YORK, UNITED STATES
- WEILL MEDICAL COLL OF CORNELL UNIV — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ANRATHER, JOSEF — WEILL MEDICAL COLL OF CORNELL UNIV
- Study coordinator: ANRATHER, JOSEF
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired brain injury