Understanding how gut bacteria influence aging in the colon
Identifying Gut Microbial Inducers of Biological Aging in the Colon
This study is looking at how the bacteria in your gut might affect the aging of your colon and the development of early signs of colon cancer, and it invites patients to help by sharing samples or information to better understand this connection.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Fred Hutchinson Cancer Center NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11075033 on NIH RePORTER |
What this research studies
This research investigates the role of gut microbes in the biological aging process of the colon, particularly focusing on how these microbes may contribute to the development of precancerous lesions known as colon adenomas. By examining the interactions between gut bacteria and cellular changes in the colon, the study aims to identify specific microbial factors that may influence the progression from early adenomas to colorectal cancer. Patients may be involved in providing samples or data that help researchers understand these mechanisms better.
Who could benefit from this research
Good fit: Ideal candidates for participation are individuals with a history of colon adenomas or those at high risk for colorectal cancer.
Not a fit: Patients without any history of colon adenomas or colorectal cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing colorectal cancer by targeting gut microbial health.
How similar studies have performed: Previous research has shown promising results in understanding the link between gut microbiomes and cancer progression, suggesting that this approach could yield valuable insights.
Where this research is happening
Seattle, United States
- Fred Hutchinson Cancer Center — Seattle, United States (Active)
Researchers
- Principal investigator: Grady, William Mallory — Fred Hutchinson Cancer Center
- Study coordinator: Grady, William Mallory
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.