Understanding how gut bacteria generate energy and their impact on health
Respiration and fitness in Bacteroides
['FUNDING_R01'] · RENSSELAER POLYTECHNIC INSTITUTE · NIH-11134579
This study is looking at how certain bacteria in our gut, called Bacteroides, produce energy and how that affects both the bacteria and our overall health, using lab techniques and mouse models to learn more about their energy-making processes.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | RENSSELAER POLYTECHNIC INSTITUTE (nih funded) |
| Locations | 1 site (TROY, UNITED STATES) |
| Trial ID | NIH-11134579 on ClinicalTrials.gov |
What this research studies
This research investigates the energy-generating processes of Bacteroides, a dominant group of bacteria in the human gut. It aims to understand how these processes support bacterial fitness and influence host health. The study will utilize genetics, biochemistry, and mouse models to explore the respiratory pathways of Bacteroides, focusing on specific components like the NUO complex and their role in energy production. By uncovering these mechanisms, the research seeks to provide insights into the complex interactions between gut bacteria and human health.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with gastrointestinal disorders or those interested in gut microbiome health.
Not a fit: Patients who do not have any gastrointestinal issues or are not interested in the role of gut bacteria in health may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of gut health and potential new treatments for gut-related conditions.
How similar studies have performed: Other research has shown promising results in understanding gut microbiota and their metabolic processes, indicating that this approach has potential for significant findings.
Where this research is happening
TROY, UNITED STATES
- RENSSELAER POLYTECHNIC INSTITUTE — TROY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BARQUERA, BLANCA — RENSSELAER POLYTECHNIC INSTITUTE
- Study coordinator: BARQUERA, BLANCA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.