Understanding how gut bacteria compete and adapt to each other

Mechanisms of adaptation to interbacterial antagonism by the human gut microbiota

['FUNDING_OTHER'] · DARTMOUTH COLLEGE · NIH-10894117

This study looks at how different bacteria in your gut, especially a group called Bacteroidales, work together and compete for space and resources, which can impact your gut health, and it hopes to find out how some bacteria can protect themselves from others to help us understand more about our gut and overall health.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorDARTMOUTH COLLEGE (nih funded)
Locations1 site (HANOVER, UNITED STATES)
Trial IDNIH-10894117 on ClinicalTrials.gov

What this research studies

This research investigates the interactions between different types of bacteria in the human gut, particularly focusing on a group called Bacteroidales. It explores how these bacteria use a specialized system to compete for resources and space, which can affect overall gut health. By examining the genetic mechanisms behind these interactions, the research aims to uncover how certain bacteria can neutralize threats from their competitors. This could lead to a better understanding of the gut microbiome's role in human health and disease.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults over 21 years old who are interested in understanding their gut health and microbiome.

Not a fit: Patients with no interest in gut health or those who are not adults may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for manipulating gut bacteria to improve health outcomes.

How similar studies have performed: Previous research has shown promising results in understanding bacterial interactions in the gut, suggesting that this approach could yield valuable insights.

Where this research is happening

HANOVER, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.