Understanding how gut bacteria communicate with the body through electrical signals
Official title: Characterizing bioelectrical signaling between the gut microbiota and the host
Funded at Indiana University Indianapolis · NIH-10939992 · Data updated 2026-11-12
This study is looking at how the bacteria in your gut talk to your body using electrical signals, which could help us understand gut health better and find new ways to treat gut-related issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project start | July 1, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $388,135 |
| NIH project number | 1R35GM154890-01 |
| Project ID | NIH-10939992 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with gastrointestinal disorders or those interested in gut health.
✕Less likely to help
Patients with no gastrointestinal issues or those not interested in microbiota-related health may not benefit from this research.
What this research studies
This research investigates the complex ways in which gut microbiota and the human body communicate using bioelectrical signals. By exploring the interactions between gut bacteria and host cells, the study aims to uncover the mechanisms behind these communications at both cellular and molecular levels. The researchers will utilize advanced tools and techniques to analyze how these signals can be modulated, potentially leading to new insights into gut health and disease. This innovative approach seeks to bridge the gap between microbiology and biophysics, focusing on the role of bioelectricity in gut-host interactions.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for gastrointestinal disorders and improve overall gut health.
How similar studies have gone: While the specific focus on bioelectrical signaling between gut microbiota and hosts is relatively novel, preliminary studies have shown promise in understanding microbial interactions and their implications for health.
Where this research is happening
-
Indiana University Indianapolis
Indianapolis, United States Active
Researchers
- Principal investigator: Needham, Brittany — Indiana University Indianapolis
- Study coordinator: Needham, Brittany
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.