Understanding how gut bacteria and their products interact and affect health
Co-informed prediction of microbiome-metabolome interactions through novel transfer learning models
This study is looking at how the bacteria in your gut affect your health, and it aims to help people understand their unique gut bacteria better so they can receive more personalized treatments.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-11121534 on NIH RePORTER |
What this research studies
This research focuses on the gut microbiome, which consists of various bacteria that play a crucial role in human health through their metabolites. By developing advanced statistical models, the research aims to analyze complex interactions between these microbes and their metabolites, even when data is limited. Patients may benefit from insights into how their gut bacteria influence health conditions, leading to more personalized treatment approaches. The study will utilize data from existing microbiome projects to enhance the understanding of these interactions.
Who could benefit from this research
Good fit: Ideal candidates include individuals with gastrointestinal disorders or those interested in understanding the impact of their gut microbiome on overall health.
Not a fit: Patients without any gastrointestinal issues or those not interested in microbiome research may not find this study beneficial.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic and therapeutic strategies based on individual microbiome profiles.
How similar studies have performed: Previous studies have shown promise in understanding microbiome-metabolome interactions, but this approach using transfer learning is relatively novel.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Wang, Yue — University of Colorado Denver
- Study coordinator: Wang, Yue
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.