Understanding how gut bacteria and diet affect body weight
Defining the Quantitative Functional Mechanisms that Underly Gut Microbiome-Diet Interactions Contributing to Human Energy Balance
['FUNDING_R01'] · ADVENTHEALTH ORLANDO · NIH-11136388
This study is looking at how the bacteria in our gut and what we eat can affect our weight, and it’s for anyone interested in understanding how different diets might help with managing obesity.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ADVENTHEALTH ORLANDO (nih funded) |
| Locations | 1 site (ORLANDO, UNITED STATES) |
| Trial ID | NIH-11136388 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between the gut microbiome and energy balance in humans, particularly how different diets influence body weight. By conducting a controlled feeding study, researchers will analyze how specific dietary components affect energy intake, expenditure, and fecal energy loss. The study aims to uncover the mechanisms through which gut bacteria interact with diet to impact weight management, potentially leading to new therapeutic approaches for obesity.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals struggling with obesity or those interested in understanding how diet affects their weight.
Not a fit: Patients who are not overweight or do not have concerns related to body weight may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative dietary strategies or microbiome-targeted therapies for effective weight management.
How similar studies have performed: Previous research has shown promising results in understanding the role of the gut microbiome in weight regulation, but this study aims to provide deeper insights into the specific mechanisms involved.
Where this research is happening
ORLANDO, UNITED STATES
- ADVENTHEALTH ORLANDO — ORLANDO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CORBIN, KAREN DAVIDOWITZ — ADVENTHEALTH ORLANDO
- Study coordinator: CORBIN, KAREN DAVIDOWITZ
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.