Understanding how gut bacteria affect rheumatic diseases
Core 2 - Mucosal Immunobiology Core (MIC)
This study is looking at how the tiny germs in our bodies and our immune system work together to affect conditions like rheumatoid arthritis and spondyloarthritis, and it's for patients who want to help researchers learn more by sharing samples like stool and oral tissues.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-10908354 on NIH RePORTER |
What this research studies
This research focuses on the role of microbiota and mucosal immunology in the development of rheumatic diseases like rheumatoid arthritis and spondyloarthritis. It aims to enhance our understanding of how host-microbe interactions influence these conditions by providing consultation and discounted services for analyzing biospecimens. The project will bring together experts in microbiome research, immunology, and data analysis to collaborate on innovative methods for studying these interactions. Patients' samples, such as feces and oral tissues, will be analyzed to uncover important insights into disease mechanisms.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with rheumatoid arthritis or spondyloarthritis who are willing to provide biospecimens for analysis.
Not a fit: Patients without rheumatic diseases or those not interested in participating in biospecimen collection may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating rheumatic diseases by targeting microbiota.
How similar studies have performed: Previous research has shown promising results in understanding the microbiome's role in rheumatic diseases, indicating that this approach has potential for success.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Lozupone, Catherine — University of Colorado Denver
- Study coordinator: Lozupone, Catherine
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.