Understanding how gut bacteria affect nutrition and health

CyberGut: towards personalized human-microbiome metabolic modeling for precision health and nutrition

['FUNDING_R01'] · INSTITUTE FOR SYSTEMS BIOLOGY · NIH-11085139

This study is looking at how the bacteria in your gut affect digestion and health, and it aims to create a personalized tool called 'CyberGut' that helps people understand how their unique gut bacteria and diet work together to influence their health.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorINSTITUTE FOR SYSTEMS BIOLOGY (nih funded)
Locations1 site (SEATTLE, UNITED STATES)
Trial IDNIH-11085139 on ClinicalTrials.gov

What this research studies

This research investigates the role of the gut microbiome in digestion and nutrient absorption, focusing on how variations in gut bacteria can influence individual health outcomes. By analyzing data from over 3,000 adults, the study aims to create a personalized metabolic model called 'CyberGut' that integrates dietary information and microbiome composition. This model will help researchers understand how different diets interact with gut bacteria to affect metabolism and overall health. Patients may benefit from insights into how their unique gut microbiome affects their nutritional needs and health.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults over 21 years old who are interested in understanding how their gut microbiome affects their health and nutrition.

Not a fit: Patients with severe gastrointestinal disorders or those who are not able to provide dietary or microbiome data may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to personalized dietary recommendations that optimize health based on individual microbiome profiles.

How similar studies have performed: Previous research has shown promising results in understanding the relationship between gut microbiota and health, indicating that this approach has potential for success.

Where this research is happening

SEATTLE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.