Understanding how gut bacteria affect nutrition and health
Official title: CyberGut: towards personalized human-microbiome metabolic modeling for precision health and nutrition
Funded at Institute for Systems Biology · NIH-11085139 · Data updated 2026-11-12
This study is looking at how the bacteria in your gut affect digestion and health, and it aims to create a personalized tool called 'CyberGut' that helps people understand how their unique gut bacteria and diet work together to influence their health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Institute for Systems Biology NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | July 1, 2022 |
| Project end | April 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $508,627 |
| NIH project number | 5R01DK133468-04 |
| Project ID | NIH-11085139 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults over 21 years old who are interested in understanding how their gut microbiome affects their health and nutrition.
✕Less likely to help
Patients with severe gastrointestinal disorders or those who are not able to provide dietary or microbiome data may not benefit from this research.
What this research studies
This research investigates the role of the gut microbiome in digestion and nutrient absorption, focusing on how variations in gut bacteria can influence individual health outcomes. By analyzing data from over 3,000 adults, the study aims to create a personalized metabolic model called 'CyberGut' that integrates dietary information and microbiome composition. This model will help researchers understand how different diets interact with gut bacteria to affect metabolism and overall health. Patients may benefit from insights into how their unique gut microbiome affects their nutritional needs and health.
Why it matters
Potential benefit: If successful, this research could lead to personalized dietary recommendations that optimize health based on individual microbiome profiles.
How similar studies have gone: Previous research has shown promising results in understanding the relationship between gut microbiota and health, indicating that this approach has potential for success.
Where this research is happening
-
Institute for Systems Biology
Seattle, United States Active
Researchers
- Principal investigator: Gibbons, Sean Michael — Institute for Systems Biology
- Study coordinator: Gibbons, Sean Michael
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.