Understanding how gut bacteria affect immune development in premature infants
Official title: Defining the role of premature infant microbial dysbiosis in mediating immune development and response to infection
Funded at Weill Medical Coll of Cornell Univ · NIH-10826946 · Data updated 2026-11-12
This study is looking at how the bacteria in the guts of premature babies can affect their immune systems and make them more vulnerable to infections like RSV, with the goal of finding ways to help them stay healthier.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | November 1, 2024 |
| Project end | October 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $85,864 |
| NIH project number | 1F32HD112151-01A1 |
| Project ID | NIH-10826946 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are premature infants who are at risk for respiratory infections and related health issues.
✕Less likely to help
Patients who are full-term infants or those without a history of respiratory issues may not benefit from this research.
What this research studies
This research investigates the role of the gut microbiome in the immune system development of premature infants. It focuses on how changes in gut bacteria can influence the immune response to infections, particularly respiratory syncytial virus (RSV). By studying the interactions between immune cells and gut microbes, the research aims to uncover why premature infants are more susceptible to severe infections and long-term respiratory issues. The approach includes analyzing the immune responses of these infants to better understand the link between gut health and respiratory outcomes.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing respiratory infections and related complications in premature infants.
How similar studies have gone: Previous research has shown that alterations in the gut microbiome can significantly impact immune responses, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Weill Medical Coll of Cornell Univ
New York, United States Active
Researchers
- Principal investigator: Brown, Julia — Weill Medical Coll of Cornell Univ
- Study coordinator: Brown, Julia
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.