Understanding how gut bacteria affect health and disease
Human microbiome metabolites in health and disease
This study is looking at how the bacteria in our gut affect our health by changing substances our bodies make, like vitamins and steroids, and it aims to find new ways to help people feel better based on these discoveries.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard Medical School NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10842312 on NIH RePORTER |
What this research studies
This research investigates the complex interactions between the human microbiome and our health by focusing on the metabolites produced by gut bacteria. The team aims to uncover how these bacterial transformations of host-produced molecules, like steroids and vitamins, influence our physiology and contribute to various diseases. By studying these interactions, the research seeks to identify potential therapeutic targets and improve health outcomes. Patients may benefit from insights into how their gut microbiome affects their health and the development of new treatments based on these findings.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with conditions related to gut health, such as diabetes or inflammatory bowel diseases.
Not a fit: Patients without any gastrointestinal issues or those not affected by the conditions being studied may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing and treating diseases linked to gut microbiome imbalances.
How similar studies have performed: Previous research has shown promising results in understanding the role of gut microbiome metabolites in health, indicating that this approach has potential for significant breakthroughs.
Where this research is happening
Boston, United States
- Harvard Medical School — Boston, United States (Active)
Researchers
- Principal investigator: Devlin, Abigail Sloan — Harvard Medical School
- Study coordinator: Devlin, Abigail Sloan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.