Understanding how gut bacteria affect gastrointestinal diseases in veterans.
Official title: BCCMA: Targeting Gut-Microbiome in Veterans Deployment Related Gastrointestinal and Liver Diseases; CMA1- The Role of GWI Gut Microbiome in Susceptibility to Diarrheal Diseases
Funded at Jesse Brown VA Medical Center · NIH-10950290 · Data updated 2026-11-12
This study is looking at how the bacteria in the gut might affect stomach and liver problems in veterans, especially those with Gulf War Illness, to find new ways to help improve their health and ease symptoms like diarrhea and inflammatory bowel diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Jesse Brown VA Medical Center NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | October 1, 2022 |
| Project end | September 30, 2026 |
| Funding year | 2025 |
| NIH project number | 5I01BX005862-03 |
| Project ID | NIH-10950290 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are veterans experiencing gastrointestinal issues, particularly those with Gulf War Illness.
✕Less likely to help
Patients who do not have gastrointestinal or liver diseases, or who are not veterans, may not benefit from this research.
What this research studies
This research investigates the role of the gut microbiome in gastrointestinal and liver diseases among veterans, particularly those affected by Gulf War Illness (GWI). The study aims to explore how changes in gut bacteria may contribute to conditions like diarrhea and inflammatory bowel diseases, which are common in this population. By analyzing the gut microbiome, researchers hope to identify potential new treatments that could alleviate symptoms and improve health outcomes for veterans. The approach includes examining the relationship between gut bacteria and disease susceptibility, with a focus on developing biotherapeutics.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly improve the quality of life for veterans suffering from gastrointestinal diseases.
How similar studies have gone: Previous research has shown promising results in understanding the gut microbiome's role in gastrointestinal diseases, indicating that this approach could be beneficial.
Where this research is happening
-
Jesse Brown VA Medical Center
Chicago, United States Active
Researchers
- Principal investigator: Dudeja, Pradeep K — Jesse Brown VA Medical Center
- Study coordinator: Dudeja, Pradeep K
Related research
Other NIH-funded projects on the same topics.
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Gut health and PTSD in veterans with inflammatory bowel disease
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Gut microbes and diarrhea risk in Gulf War veterans
This project looks at whether changes in gut microbes explain why Gulf War and other deployed veterans get frequent diarrhea and related gut problems.
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Gut microbiome, fiber, and short-chain fatty acids in Veterans with Gulf War Illness
This project tests whether Veterans with Gulf War Illness who have gut problems have lower levels of helpful gut bacteria and short-chain fatty acids, and whether eating more fiber relates to fewer digestive symptoms.
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Understanding Gut Health in Veterans with Deployment-Related GI and Liver Conditions
This project explores how the gut microbiome and PTSD might be connected to inflammatory bowel disease and other digestive issues in Veterans.
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Investigating the gut microbiome's role in liver disease and PTSD among US Veterans
This study is looking at how PTSD might impact the health of veterans' livers and gut bacteria, hoping to find new ways to help improve their overall health by understanding the connections between these areas.
-
Investigating the gut microbiome's role in gastrointestinal issues among Gulf War veterans
This study is looking at how the bacteria in your gut might influence stomach and liver problems in veterans with Gulf War Illness, and it hopes to find ways to improve your gut health and reduce symptoms by examining your diet and gut bacteria.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.